Vitamin K1 10mg/1ml Injection

 Composition:

• **Active Ingredient:**
• Phytonadione (Vitamin K1) - 10 mg/ml
• **Excipients:**
• Benzyl alcohol (as a preservative)
• Sodium chloride (for isotonicity)
• Water for injection (q.s. to 1 ml)

#### Dosage:

• **Adults:**
• **Prophylaxis of Vitamin K deficiency:** 10 mg to 20 mg administered intramuscularly or intravenously, depending on the clinical situation.
• **Treatment of anticoagulant overdose (e.g., warfarin):** 1 to 10 mg administered intravenously, with repeat doses as necessary based on INR levels.
• **Pediatrics:**
• **Newborns (for prevention of Vitamin K deficiency bleeding):** 1 mg intramuscularly at birth, with a possible additional dose at 1 week of age if indicated.
• **Infants and children:** Dosage should be determined by a healthcare professional based on the specific clinical scenario.

#### Indications:

• **Prophylaxis and Treatment of Vitamin K Deficiency:**
• Used in patients with malabsorption syndromes, liver disease, or those on long-term antibiotic therapy that may disrupt gut flora.
• **Management of Anticoagulant Overdose:**
• Administered in cases of excessive anticoagulation due to warfarin or other vitamin K antagonists.
• **Prevention of Hemorrhagic Disease of the Newborn:**
• Administered to newborns to prevent Vitamin K deficiency bleeding, a serious condition that can lead to bleeding in the brain and other organs.
• **Other Indications:**
• May be used in certain cases of coagulopathy or as directed by a healthcare provider.

#### Note:

• Dosage adjustments may be necessary based on individual patient factors, including age, weight, and underlying health conditions.
• Always consult a healthcare professional for appropriate dosing and administration routes tailored to the patient's needs.